在职教师
乔永霞

 

职称: 讲师                              

学位/学历: 博士

Email: Yongxia.qiao@shsmu.edu.cn

 

 

        具有临床医学专业和流行病与卫生统计背景,从事工作涉及心脑血管疾病、代谢性疾病、药物流行病、营养及运动干预、妇产科流行病等方面的研究。 2008年硕士在读期间,以第一名的成绩转为提前攻读博士生,2010-2012年国家公派赴美国马萨诸塞州大学医学院留学1.5年。2012年6月毕业于同济大学医学院,或内科学博士学位。2006-2010年独立完成两项上海市卫生局级课题,2010-2012年在美国期间参与多项美国NIH资助的项目,包括美国著名的女性研究项目“妇女健康启动(WHI)”,和其他几项R01和R21项目。2013年获得国家自然科学基金一项,2008年至今已发表文章21篇,其中第一作者SCI文章6篇(累计影响因子13分)。
 
主要研究方向
1. 肿瘤流行病学
2. 心血管疾病流行病学
3. 妇产科流行病学
4. 行为干预
 
主要研究课题
1. 上海市卫生局(2008年)项目:围产期孕妇焦虑抑郁对妊娠分娩及新生儿出生评分影响的群组研究
2. 美国妇女健康启动项目,美国国立卫生研究院N01WH22110, 24152, 32100-2,32105-6, 32108-9, 32111-13, 32115, 32118-32119,32122, 42107-26, 42129-32, and 44221.
3. 国家自然科学基金(81301689):糖尿病AGE/AGER信号通路调控YAP活性与肝癌发生的机制及流行病学研究
 
主要研究成果
1. Wang J*, Qiao YX*, Sun F, Wan Y, Huang T, Ye T, Yu Y. Identification and characterization of mouse Gas6 promoter. Biochem Biophys Res Commun. 2008 Jul 4;371(3):567-72. (*共同第一作者)
2. 李觉,乔永霞,孙英贤,郭晓铭,庞文跃,罗盈怡,胡大一.踝臂指数诊断下肢动脉疾病的敏感性和特异性.中华老年医学杂志.2008;27(9):641-644   
3. Yongxia Qiao, Jing Wang, Jue Li, Alimujiang Ablat. The Prevalence and Related Risk Factors of Anxiety and Depression symptoms among Chinese pregnant women in Shanghai. Australian and New Zealand Journal of Obstetrics and Gynaecology, 2009;49(2):185-190.
4. 李觉,胡大一,庞文跃,郭晓铭,赵明中,罗盈怡,乔永霞,孙英贤. 踝臂指数与外周血管狭窄的相关研究.中华心血管病杂志.2008;36(6):514-516
5. 王净 乔永霞 李觉.早孕终止妊娠妇女焦虑抑郁情绪现患率和相关危险因素分析.同济大学学报(医学版)2009 30(1) :144-148
6. Luo Y, Li X, Li J, Wang X, Xu Y, Qiao Y, Hu D, and Ma Y. Peripheral Arterial Disease, Chronic Kidney Disease, and Mortality: The Chinese ankle brachial index cohort study. Vascular Medicine, 2010, 5(2):101-112.
7. Luo Y, Li X, Li J, Wang X, Qiao Y, Hu D, Merriam PA, and Ma Y. Combined effects of smoking and peripheral arterial disease on all-cause and cardiovascular disease mortality in a Chinese male cohort. Journal of Vascular Surgery, 2010, 51(3):673-8. 
8. Jiayi Wang, Xiangfan Liu, Huacheng Wu, Peihua Ni, Zhidong Gu, Yongxia Qiao, Ning Chen, Fenyong Sun, and Qishi Fan. CREB upregulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer. (2010), Nucleic Acids Res. 38: 5366-5383. 
9. Huiping Xue*, Yongxia Qiao*, Peihua Ni, Jiayi Wang, Changqiang Chen, Gang Huang. A CRE that binds CREB and contributes to PKA-dependent regulation of the proximal promoter of human RAB25 gene. (2011), Int. J. Biochem. Cell. Biol., 43: 348-357. (*共同第一作者)
10. Wenhao Weng, Qinyuan Yang, Miaolong Huang, Yongxia Qiao, Yuan Xie, Yongchun Yu, An jing Zhi Li. c-Myc inhibits TP53INP1 expression via promoter methylation in esophageal carcinoma. (2011). Biochem. Biophys. Res. Commun., 405: 278-284. 
11. Jiayi Wang, Peihua Ni, Zhidong Gu, Yongxia Qiao, Xiangfan Liu, Changqiang Chen, Qishi Fan. NF-kappaB P50/P65 hetero-dimer mediates differential regulation of CD166/ALCAM expression via interaction with micoRNA-9 after serum deprivation, providing evidence for a novel negative auto-regulatory loop. (2011). Nucleic Acids Res. 39: 6440-6455. 
12. Culver AL, Ockene IS, Balasubramanian R, Sepavich DM, Wactawski-Wende J, Olendzki BC, Manson J, Rahilly-Tierny C, Liu S, Qiao Y, Merriam P, Thomas F, Berger J, Ockene JK, Curb D and Ma Y. Statin Use and Risk of Diabetes in Postmenopausal Women. Archives of Internal Medicine. 2012 Jan 23;172(2):144-52
13. 乔永霞,李觉,王净。孕产期焦虑抑郁对妊娠、分娩及新生儿的影响(综述)。中华围产医学杂志,2011,14:649-53
14. Qiao Y, Wang J, Li J, Wang J. Effects of depressive and anxious symptoms during pregnancy on pregnant, obstetric and neonatal outcomes: a follow-up study. Journal of Obstetrics and Gynaecology. 2012 Apr;32(3):237-40.
15. Carmody JF, Olendzki BC, Merriam PA, Liu Q, Qiao Y. Ma Y. A Novel Measure of Dietary Change in a Prostate Cancer Dietary Program Incorporating Mindfulness Training. Journal of the Academy of Nutrition and Dietetics. 2012 Nov;112(11):1822-7
16. Ma Y, Hébert JR, Manson JE, Balasubramanian R, Liu S, Lamonte M, Ockene JK, Qiao Y, Olendzki BC, Schneider KL, Bird CE, Rosal MC, Wactawski-Wende J, Stefanick M, Phillips LS, Sepavich DM, Ockene IS, Kaplan RC, Sarto GE, Garcia L, Howard BV. Determinants of Racial/Ethnic Disparities in Incidence of Clinical Diabetes in Postmenopausal Women in the United States: The Women’s Health Initiative 1993- 2009.Diabetes Care。November 2012 vol. 35 no. 11 2226-2234
17. Qiao Y, Tinker L, Olendzki B, Hébert JR, Balasubramanian R, Rosal MC, Hingle M, Song Y, Schneider KL, Liu S, Sims S, Ockene JK, Sepavich DM, Shikany JM, Persuitte G, and Ma Y*. Racial/Ethnic disparities in association between dietary quality and incident diabetes in postmenopausal women in the United States: The Women’s Health Initiative 1993- 2005. Ethnicity and Health. 2013, DOI:10.1080/13557858.2013.797322 (IF:1.2)
18. Jiayi Wang, Lifang Ma, Yue Zhang, Yongxia Qiao, Wenhao Weng, Jiangtu He, Qiuhui Pan, Yongchun Yu, Fenyong Sun. (2013). Mutual interaction between YAP and CREB promotes tumorigensis in liver cancer. Hepatology 58: 1011-1020 (IF: 11.665).
19. Jiayi Wang, Yue Zhang, Wenhao Weng, Yongxia Qiao, Lifang Ma, Weifan Xiao, Yongchun Yu, Qiuhui Pan2, and Fenyong Sun. (2013) Impaired phosphorylation and ubiquitination by P70 S6 kinase (P70S6K) and Smad ubiquitination regulatory factor 1 (Smurf1) promotes Tribbles homolog 2 (TRIB2) stability and carcinogenic property in liver cancer. J. Biol Chem. Accepted. In press. DOI: 1074/jbc. M113.503292.
20. Jiayi Wang*, Hongmei Wang*, Yongxia Qiao*, Wenhao Weng, Xiangfan Liu, Yue Zhang, Lifang Ma, Weifan Xiao, Wenjun Yu, Qinghua Chu, Qiuhui Pan, and Fenyong Sun. (2013) Mutual inhibition between YAP and SF2 maintains long non-coding RNA, Malat1 induced tumorigenesis in liver cancer. Exp. Cell Res. In revision (* Contributed equally).
 
教学工作                                                      
1. 本科生、研究生流行病学
2. 本科生医学统计学
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